Autoimmune disorders encompass a wide range of immunological diseases that affect 4 to 10% of the population worldwide. They occur when immunological tolerance toward self-antigens is broken, resulting in immune responses against cells, tissues, or organs that lead to tissue dysfunction and/or destruction. The goal of autoimmune disease therapy is to restore tolerance to the self-antigen that causes the pathology by targeting autoreactive T cells while preserving immune competence to prevent infections and malignancies. The main challenge of this endeavor resides in choosing the mode by which the disease-driving antigen is delivered so that it can initiate the removal or reprogramming of the autoreactive T cells or the induction and/or expansion of antigen-specific regulatory T (Treg) cells to suppress autoreactive T cells. Although the potential of antigenbased immunotherapy approaches to restore tolerance have been demonstrated for the treatment of immunoglobulin E (IgE) – mediated peanut allergy (1), antigen therapies for autoimmune disorders are still being developed.
Browsing: Science/Tech & Innovation/R&D
The Director of Biotechnology, Precious Cornerstone University, Ibadan, Prof. Charles Adetunji says biotechnology innovations can help in alleviating poverty and creating impact in the community.
The Director, MacArthur Foundation Africa,Dr Kole Shettima on Wednesday said it had supported Ahmadu Bello University (ABU), Zaria with over $15, 538, 896 to enhance learning and research.
War is raging in Ukraine and Gaza. The United States is headed for another tight, and heated, presidential election. Political upheaval is taking place in countries around the globe. And journalists are tasked with covering it all, despite the rise in threats to their physical and digital security, which are often connected.
The National Board for Technical Education (NBTE) says it’s spearheading the transformation of Nigeria’s educational sector through the innovative application of data science.
He holds a certificate in primary education, which he obtained at the Aljannare Primary School in Tambuwal local government area of Sokoto state. The 52-year-old Usmanu Abubakar has the ability of fabricating all types of machines, including thresher, grains dehulling and for mining operations.
An artificial intelligence specialist, Oludayo Ojerinde, has unveiled a health-focused chatbot to address people’s healthcare needs.
Elon Musk’s electronic company, Tesla is the largest comoaby by market cap, World of Statistics twitted on its X handle @stats_feed on Friday.
A Chinese and German collaborative team have developed a soft tiny robot with a spring-like structure that can sense, grasp and move.
The Centre for Girls’ Education (CGE), Zaria, Kaduna State, has empowered over 200,000 vulnerable girls with skills and set venture into free Artificial Intelligence (AI) training to enable the beneficiaries harness their potentials.