Chinese scientists identify biomarker for early detection of Alzheimer’s disease
Chinese scientists have identified a biomarker that can facilitate early detection and intervention of Alzheimer’s Disease (AD) about five to seven years in advance.
Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory, thinking skills and the ability to carry out simple tasks.
Scientists from the Beijing-based Xuanwu Hospital of the Capital Medical University, have found that blood neuro-exosomal synaptic proteins, can be a promising biomarker for the disease.
Xinhua reports Jia Jianping, Leader of the Research Team and a professor at Xuanwu Hospital, as saying that there is no effective drug that can cure Alzheimer’s disease.
Many drugs for Alzheimer’s disease have failed in clinical trials.
“The main reason could be that the subject’s disease is at a late stage”, he said.
Jia and his team collected a total of 739 subjects by following people who had normal cognitive function between five and seven years ago and found that blood neuro-exosomal synaptic proteins could be used as biomarkers to predict AD five to seven years in advance.
“Effective diagnosis of early or asymptomatic Alzheimer’s disease can gain time for early intervention, increasing the effectiveness of treatment and reducing the incidence of the disease,” said Jia.
The research was published in the journal Alzheimer’s & Dementia.
At least 50 million people worldwide have dementia and Alzheimer’s disease is the root cause behind 60 per cent to 70 per cent of the cases, according to the World Health Organization.