AsheNews

Top Menu

  • Advert Rates

Main Menu

  • Home
  • General News
  • AGRICULTURE
  • Business/Banking & Finance
  • Entertainments & Sports
  • HEALTH
  • International
  • Investigation
  • Law & Human Rights
  • Advert Rates

logo

Header Banner

AsheNews

  • Home
  • General News
  • AGRICULTURE
  • Business/Banking & Finance
  • Entertainments & Sports
  • HEALTH
  • International
  • Investigation
  • Law & Human Rights
  • JJC Skillz announces separation from actress wife, Funke Akindele-Bello

  • One memorises Holy Qur’an, as 56 Sokoto medical students graduate with First Class Degrees from India, Sudan

  • Nigeria’s refineries producing zero litre of fuel – NNPC

  • Niger declares 2-day public holidays for civil servants to acquire PVC

  • Senate confirms President Buhari’s 7 ministerial nominees [LIST]

HEALTH & HEALTHY LIVING
Home›HEALTH & HEALTHY LIVING›Antimicrobial ingredient in toothpastes may have adverse colonic effects: study

Antimicrobial ingredient in toothpastes may have adverse colonic effects: study

By Abdallah el-Kurebe
May 31, 2018
202
0

American and Chinese scientists have found that an antimicrobial ingredient commonly used in hand soaps and toothpastes could have adverse effects on colonic inflammation and colon cancer by altering gut microbiota, the microbes found in people’s intestines.

A study published in the journal Science Translational Medicine revealed that short-time treatment with low-dose triclosan led to low-grade colonic inflammation, and exaggerated disease development of colitis and colitis-associated colon cancer in mice.

“These results, for the first time, suggest that triclosan could have adverse effects on gut health,” said Zhang Guodong, assistant professor of food science at the University of Massachusetts Amherst, the paper’s senior author.

Zhang told Xinhua, “The toothpaste we use can enter into the intestinal tract, then impacting the gut microbiota.”

Triclosan is among the most widely used antimicrobial ingredients and is found in more than 2,000 consumer products and a National Health and Nutrition Examination survey showed that triclosan was detected in about 75 per cent of the urine samples of individuals tested in the U. S. and it is among the top ten pollutants found in U.S. rivers.

“Because this compound is so widely used, our study suggests that there is an urgent need to further evaluate the impact of triclosan exposure on gut health in preparation for the potential establishment of further regulatory policies,” said Yang Caixia, a postdoctoral fellow in Zhang’s laboratory and the paper’s first author.

Zhang’s team and Chinese researchers including those from Xi’an Jiaotong University investigated the effects of triclosan on colonic inflammation and colon cancer using several mouse models.

They reported that in all mouse models tested, triclosan promoted colonic inflammation and colon tumorigenesis.

The research team found that gut microbiota was critical for the observed adverse effects of triclosan, since feeding triclosan to mice reduced the diversity and changed the composition of the gut microbiome.

However, triclosan had no effect in a germ-free mouse model where there is no gut microbiome present, nor in a genetically engineered mouse model where there is no Toll-like receptor 4 (TLR4), an important mediator for host-microbiota communications.

“This is strong evidence that gut microbiota is required for the biological effects of triclosan,” Zhang said.

This study observed that triclosan altered mouse gut microbiota, increased inflammation, increased the severity of colitis symptoms and spurred colitis-associated colon cancer cell growth. (Xinhua)

TagsantimicrobialScience Translational MedicineToothpasteUniversity of Massachusetts AmherstZhang Guodong
Previous Article

WHO says 1.1bn people are smokers globally

Next Article

Germany: Hamburg becomes 1st city to ban ...

Abdallah el-Kurebe

Related articles More from author

  • GENERAL NEWSHEALTH & HEALTHY LIVING

    Why we lost 18 patients to COVID-19 – CMD UCH

    August 14, 2020
    By Abdallah el-Kurebe
  • GENERAL NEWSHEALTH & HEALTHY LIVING

    COVID-19: Nigeria records a new spike of 4,035 infections

    December 23, 2021
    By NewsDesk
  • HEALTH & HEALTHY LIVINGSCIENCE AND TECHNOLOGY

    Tumor: Nigeria’s JUTH undertakes first brain surgery using drilling machine

    May 26, 2019
    By Abdallah el-Kurebe
  • GENERAL NEWSHEALTH & HEALTHY LIVING

    FG approves new test kit for HIV

    September 8, 2020
    By Abdallah el-Kurebe
  • ECONOMYHEALTH & HEALTHY LIVINGOIL & GAS/MINERAL RESOURCES

    COVID-I9: How pandemic impacted positively on Oil and Gas Sector – Minister

    June 27, 2021
    By Editor
  • GENERAL NEWSHEALTH & HEALTHY LIVINGPRESIDENCY

    Nigeria’s vice president reaffirms zero tolerance to gender-based violence 

    August 3, 2021
    By Editor

Leave a reply Cancel reply

You may interested

  • DISASTER/ACCIDENT/FRSCGENERAL NEWSSECURITY

    #EndSARS: Buhari commends Kebbi youths, as Malami donates more to flood victims

  • ELECTIONSGENERAL NEWS

    INEC declares PDP candidate winner of supplementary election in Zamfara

  • GENERAL NEWSINTERNATIONALMEDIA/PR/JOURNALISM

    Ukraine: YouTube blocks channels linked to Russia’s RT, Sputnik across Europe

Latest News

  • June 30, 2022

    JJC Skillz announces separation from actress wife, Funke Akindele-Bello

  • June 29, 2022

    One memorises Holy Qur’an, as 56 Sokoto medical students graduate with First Class Degrees from India, Sudan

  • June 29, 2022

    Nigeria’s refineries producing zero litre of fuel – NNPC

  • June 29, 2022

    Niger declares 2-day public holidays for civil servants to acquire PVC

  • June 29, 2022

    Senate confirms President Buhari’s 7 ministerial nominees [LIST]

Latest Comments

  • Aliyu Buba Maigoro
    on
    April 3, 2022
    The unfortunate thing is, does your votes count?!

    NULGE TO NIGERIANS: Don’t re-elect governors opposing LG autonomy

  • mubashshir Muhammad sani
    on
    March 22, 2022
    Good news

    FAAC: Federal, states, local governments share N590.546bn as February allocation 

  • AA Sadeeq
    on
    March 16, 2022
    And the US and all its political leaders?

    Biden changes stance, calls Putin ‘a war criminal’

  • Umar Ahmad
    on
    March 12, 2022
    What the USA refused to happen to her in 1960s, she is now trying to force ...

    Russia-Ukraine War: Why Nigerian govt must ban maize exports – Dangote

  • mohammad abubakar kudu
    on
    March 11, 2022
    Very good and updated reports..

    How governors spend security votes, NGF chairman, Fayemi reveals

About us:

ASHE (Pronounced ASH) is an acronym for Agriculture, Science, Health and Environment. Ashenewsonline brings to you news focused in these as well as Politics, Business, Economy and all other aspects of human endeavour.

We are here to feed into Nigeria’s news service chain as a frontier source for citizens journalism. Beyond mentioning, Ashenewsonline encourages people to provide story tips on human rights abuses, corruption, good governance, etc.

Contact Info:

  • No. 5, Maiduguri road 1st floor, Dogon Daji House, Sokoto
  • 07031140009
  • ashenewsonline@gmail.com
  • Recent

  • Popular

  • Comments

  • JJC Skillz announces separation from actress wife, Funke Akindele-Bello

    By NewsDesk
    June 30, 2022
  • One memorises Holy Qur’an, as 56 Sokoto medical students graduate with First Class Degrees from ...

    By NewsDesk
    June 29, 2022
  • Nigeria’s refineries producing zero litre of fuel – NNPC

    By NewsDesk
    June 29, 2022
  • Niger declares 2-day public holidays for civil servants to acquire PVC

    By NewsDesk
    June 29, 2022
  • Nigeria says 3,598 cholera deaths in 2021 unacceptable

    By Editor
    January 11, 2022
  • Nigeria’s apex bank governor tasks rice millers on FOREX, employment

    By NewsDesk
    February 2, 2022
  • COLUMN: The Craze for Easy Money in Nigeria and The Hanifa Story, By Prof. M ...

    By NewsDesk
    February 6, 2022
  • How governors spend security votes, NGF chairman, Fayemi reveals

    By NewsDesk
    March 11, 2022
  • Aliyu Buba Maigoro
    on
    April 3, 2022

    NULGE TO NIGERIANS: Don’t re-elect governors opposing LG autonomy

    The unfortunate thing is, ...
  • mubashshir Muhammad sani
    on
    March 22, 2022

    FAAC: Federal, states, local governments share N590.546bn as February allocation 

    Good news
  • AA Sadeeq
    on
    March 16, 2022

    Biden changes stance, calls Putin ‘a war criminal’

    And the US and ...
  • Umar Ahmad
    on
    March 12, 2022

    Russia-Ukraine War: Why Nigerian govt must ban maize exports – Dangote

    What the USA refused ...

Photostream

    Follow us

    © Copyright ASHENEWS. All rights reserved. Digital materials on this website may not be published, reproduced, rebroadcast, rewritten or redistributed in whole or in part without prior express written permission from PenPlus Media Consults Ltd, Publishers of AshenewsDaily.com | Powered by Growsyn Cloud Platform