The United States has committed up to $792 million over five years to support Malawi’s healthcare system under a new bilateral cooperation agreement that signals a fundamental rethink of how Washington delivers global health assistance in Africa.
The deal sits within a broader $936 million cooperation framework that combines US funding with increased Malawian domestic investment, underscoring a move away from donor-led service delivery towards shared responsibility and long-term system sustainability.
According to a statement issued by the United States Department of State on January 14, the agreement reflects Washington’s push to rewire global health funding around national ownership, stricter accountability and reduced long-term dependence on US aid.
The five-year Memorandum of Understanding (MOU) was signed with the Government of Malawi under the America First Global Health Strategy, which links overseas health spending more directly to US security interests and measurable public health outcomes.
Under the MOU, and working with Congress, the United States intends to channel up to $792 million towards Malawi’s response to HIV/AIDS, malaria and other infectious diseases, while strengthening disease surveillance and outbreak preparedness.
Malawi has committed to increasing its overall annual health spending by an additional $143.8 million over the life of the agreement, bringing the total cooperation envelope to $936 million.
US officials said the structure is designed to replace open-ended aid flows with co-investment arrangements where responsibilities and results are clearly defined on both sides.
A central pillar of the agreement is sustaining Malawi’s progress against HIV/AIDS, where gains in diagnosis, treatment and viral suppression have been cited by US officials as evidence that transition to national management is viable.
The State Department said the MOU supports Malawi’s commitment to maintaining the 95-95-95 targets for epidemic control through integrated service delivery models that will be fully sustained by the government after the agreement concludes.
Officials described the approach as critical to protecting years of donor-backed progress from reversal.
Ending parallel delivery systems
The agreement marks a deliberate shift away from parallel NGO-run delivery systems that have long operated alongside Malawi’s public health institutions.
Under the new framework, responsibility for healthcare workers, infrastructure and service delivery will increasingly sit with national authorities, restoring control and accountability to the state.
Washington argues this transition is essential to building a health system capable of responding rapidly to future pandemics and cross-border disease threats.
Beyond HIV/AIDS, the MOU covers tuberculosis, malaria, maternal and child health, polio and global health security, alongside support for digital health solutions to reach underserved rural populations.
The State Department said stronger surveillance and early warning systems in Malawi would help prevent local outbreaks from escalating into regional or global crises, directly reinforcing US public health security.
US officials indicated the Malawi agreement could serve as a model for future health partnerships across Africa as Washington aligns development assistance more closely with self-reliance and security objectives.

